Neurokinin B ( —— )

产品货号. M30062 CAS No. 86933-75-7

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HNMR

HPLC

MSDS

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产品名称

Neurokinin B
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion of gonadotropin-releasing hormone.
产品描述

Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion of gonadotropin-releasing hormone.(In Vitro):Neurokinin B (NKB) belongs to the tachykinin family of peptides that initially included the neuropeptides substance P (SP), neurokinin A (NKA), and NKB and more recently, endokinins and hemokinins. Tachykinins bind a family of G-protein-coupled receptors (GPCRs)-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.
同义词

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通路

GPCR/G Protein
靶点

Neurokinin Receptor
受体

Neurokinin receptor
研究领域

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适应症

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Navarro VM. Interactions between kisspeptins and neurokinin B. Adv Exp Med Biol. 2013;784:325-47.

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关联产品

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L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM).
Eledoisin

Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994.
Neurokinin A(4-10)

Neurokinin A (4-10) is a tachykinin NK2 receptor agonist. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) was performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle.